The overall goal of the Popovics Lab is to improve lower urinary tract symptoms (LUTS) related to prostate pathologies in the aged men population. LUTS represent a cluster of urinary problems that affects the aging male population worldwide significantly deteriorating their quality of life. Our limited knowledge on the disease pathology prevents us from developing more efficacious therapies. The mission of the lab is to identify the molecular mechanism of inflammation-induced pathological changes in the prostate through translational research and the development of animal and cellular models.