Jorge L. Jacot, PhD

<p>University of Maryland School of Medicine</p>
<p>MS,  1988,  Dept. of Anatomic Pathology</p>
<p> </p>
<p>Uniformed Services University of the Health Sciences (USUHS)</p>
<p>F. Edward Hebert School of Medicine, Bethesda, MD</p>
<p>PhD,  1993,  Dept. of Physiology</p>
<p> </p>
<p> </p>

Associate Professor

Pathology and Anatomy


Lewis Hall

757.446.5648

jacotjl@evms.edu


Previous and Present Professional Positions

 

Assistant Professor

Dept. Pathology and Anatomy, Physiological Sciences

Eastern Virginia Medical School

2007 - present

 

Assistant Professor

Dept. of Internal Medicine

Eastern Virginia Medical School (EVMS)

2004 - 2008

 

Assistant Professor

Dept. of Physiological Sciences

Eastern Virginia Medical School (EVMS)

2004 - 2008

 

Teaching Assistant/Instructor

Human Anatomy & Physiology

Univ. of Maryland at Baltimore (UMBC)

1985 - 1989

 

 

Pharmaceutical Experience

Assistant Director

Institute for Pharmaceutical Discovery (IPD): Division of Biological Science Division and Comparative Medicine.  Led an interdisciplinary research team in a multi-million dollar project for development of proprietary drug. 

Evaluated physiological parameters in animal models for drug efficacy and for clinical end-points.

Developed biomarkers for assay development and screening.  Experience with medical/regulatory writing and FDA IND submissions.

2001-2003

 

Research Scientist-Biology Department-Institutes for Pharmaceutical Discovery (IPD).

Team Leader of R&D projects.

1998-2001

 

 

Other Employment

President and CEO

Angioceutics International, LLC

2011 - present

 

Founder and senior managing partner

Yolar International Hospitality, LLC

2010 - present

 

Dept. of Health & Human Services

Commission of Public Health.Washington D.C.

1988

 

Medical Consultant

HCX, Washington D.C.

1986

 

Vol. State of MD Emergency Medical Tech/Paramedic Assistant

BCC Rescue Squad

1982 - 1984

 

 

Courses Taught

Medical Ethics

Essential Physiology & Primer for Human Anatomy

Medical Terminology

Medical Photography

Educational Methodologies

Inter Professional Education IPE

University of Pathology Informatics Certificate of Completion Program

Lab Management University Certificate of Completion Program

Graduate Seminar - Capstone

 

Undergraduate Degree

Montgomery College, Rockville, MD

AA,  General Education: Mathematics & Science

1984

 

University of Maryland, Catonsville, MD

BA,  Biological Science

1986

 

Fellowship

National Institutes of Health (NIH),  Bethesda, MD

Research Fellowship-National Eye Institute

1993 - 1998

Graduate Education

University of Maryland School of Medicine

MS,  1988,  Dept. of Anatomic Pathology

 

Uniformed Services University of the Health Sciences (USUHS)

F. Edward Hebert School of Medicine, Bethesda, MD

PhD,  1993,  Dept. of Physiology

 

 

Research Interests

Patents and Copyrights

Jacot JL, O Neill JT, Reinisch L. Noninvasive method for quantitation of oxyhemoglobin saturation by near-infrared reflectance spectrophotometry (application No. US1991000713212 filed 6/11/91, issued 6/15/93).

 

Sredy J, Jacot JL.  Methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substituted indolealkanoic acids. (No. 99,156-A).

 

Vinik AI, JacotJL. Nutraceuticals for the treatment of neuropathy (submitted May 12, 2005). 

 

Multi-year Consortium Budget Preparation and Calculation Worksheet Computer Program.  Certificate of Registration, June 19, 2006.

 

 

Marketed Accomplishments

NutriNerve:  A combination of several dietary supplement nutraceuticals prepackaged in a formulation designed for the treatment of neuropathies associated with diabetes.

 

Novel Aldose Reductase Inhibitor: Discovery of a highly potent and selective Aldose Reductase Inhibitor with IND FDA-submission and Phase I clinical trials for the treatment of chronic diabetic complications.

 

Awards

Outstanding Performer Scientist IPD/IDD Achievement Award  (2001)

 

NIH Fellows Award for Research Excellence (1996)

 

Recipient of ARVO Travel Fellowship Grant (1994 & 1996)

 

Outstanding Poster Presentation Award Graduate Research Colloquium, USUHS (1992)

 

Honorable Mention (1990) & Recipient (1991): The Emma L. Bockman Memorial Award for Excellence in Cardiovascular/Cancer Research

 

 

Presentations and Scholarships

Selected Publications

Jacot JL, Vinik AI. Diabetic Retinopathy: Unraveling the Paradoxical Effects of Intensive Insulin Treatment. Insulin 2007, vol 2. no1. 4-11.

Jacot JL, Sherris D. Role of mTOR inhibitors in the pathophysiology of diabetic retinopathy.  Journal of Ophthalmology. 2011, Article ID 589813, 19 pages.

Jacot JL, Looft-Wilson RC, Yousefieh N, Lattanzio FA, Hosseini A.  The Vasoproliferative Phase in the Oxygen-Induced Rat Model of Retinopathy of Prematurity Exhibits Concomitant Increased Expression of VEGF164 and Phosphorylation of eNOS at Serine 1179 Journal of Clinical Pathology and Laboratory Medicine 2017 vol 1 , issue 1 page 12-20.

Courses Taught

Medical Ethics

Essential Physiology & Primer for Human Anatomy

Medical Terminology

Medical Photography

Educational Methodologies

Inter Professional Education IPE

University of Pathology Informatics Certificate of Completion Program

Lab Management University Certificate of Completion Program

Graduate Seminar - Capstone

 

Undergraduate Degree

Montgomery College, Rockville, MD

AA,  General Education: Mathematics & Science

1984

 

University of Maryland, Catonsville, MD

BA,  Biological Science

1986

 

Fellowship

National Institutes of Health (NIH),  Bethesda, MD

Research Fellowship-National Eye Institute

1993 - 1998

Graduate Education

University of Maryland School of Medicine

MS,  1988,  Dept. of Anatomic Pathology

 

Uniformed Services University of the Health Sciences (USUHS)

F. Edward Hebert School of Medicine, Bethesda, MD

PhD,  1993,  Dept. of Physiology

 

 

Research Interests

Patents and Copyrights

Jacot JL, O Neill JT, Reinisch L. Noninvasive method for quantitation of oxyhemoglobin saturation by near-infrared reflectance spectrophotometry (application No. US1991000713212 filed 6/11/91, issued 6/15/93).

 

Sredy J, Jacot JL.  Methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substituted indolealkanoic acids. (No. 99,156-A).

 

Vinik AI, JacotJL. Nutraceuticals for the treatment of neuropathy (submitted May 12, 2005). 

 

Multi-year Consortium Budget Preparation and Calculation Worksheet Computer Program.  Certificate of Registration, June 19, 2006.

 

 

Marketed Accomplishments

NutriNerve:  A combination of several dietary supplement nutraceuticals prepackaged in a formulation designed for the treatment of neuropathies associated with diabetes.

 

Novel Aldose Reductase Inhibitor: Discovery of a highly potent and selective Aldose Reductase Inhibitor with IND FDA-submission and Phase I clinical trials for the treatment of chronic diabetic complications.

 

Awards

Outstanding Performer Scientist IPD/IDD Achievement Award  (2001)

 

NIH Fellows Award for Research Excellence (1996)

 

Recipient of ARVO Travel Fellowship Grant (1994 & 1996)

 

Outstanding Poster Presentation Award Graduate Research Colloquium, USUHS (1992)

 

Honorable Mention (1990) & Recipient (1991): The Emma L. Bockman Memorial Award for Excellence in Cardiovascular/Cancer Research

 

 

Presentations and Scholarships

Selected Publications

Jacot JL, Vinik AI. Diabetic Retinopathy: Unraveling the Paradoxical Effects of Intensive Insulin Treatment. Insulin 2007, vol 2. no1. 4-11.

Jacot JL, Sherris D. Role of mTOR inhibitors in the pathophysiology of diabetic retinopathy.  Journal of Ophthalmology. 2011, Article ID 589813, 19 pages.

Jacot JL, Looft-Wilson RC, Yousefieh N, Lattanzio FA, Hosseini A.  The Vasoproliferative Phase in the Oxygen-Induced Rat Model of Retinopathy of Prematurity Exhibits Concomitant Increased Expression of VEGF164 and Phosphorylation of eNOS at Serine 1179 Journal of Clinical Pathology and Laboratory Medicine 2017 vol 1 , issue 1 page 12-20.

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