Profiles
Jorge L. Jacot, PhD, MS
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Previous and Present Professional Positions
Assistant Professor
Dept. Pathology and Anatomy, Physiological Sciences
Eastern Virginia Medical School
2007 - present
Assistant Professor
Dept. of Internal Medicine
Eastern Virginia Medical School (EVMS)
2004 - 2008
Assistant Professor
Dept. of Physiological Sciences
Eastern Virginia Medical School (EVMS)
2004 - 2008
Teaching Assistant/Instructor
Human Anatomy & Physiology
Univ. of Maryland at Baltimore (UMBC)
1985 - 1989
Pharmaceutical Experience
Assistant Director
Institute for Pharmaceutical Discovery (IPD): Division of Biological Science Division and Comparative Medicine. Led an interdisciplinary research team in a multi-million dollar project for development of proprietary drug.
Evaluated physiological parameters in animal models for drug efficacy and for clinical end-points.
Developed biomarkers for assay development and screening. Experience with medical/regulatory writing and FDA IND submissions.
2001-2003
Research Scientist-Biology Department-Institutes for Pharmaceutical Discovery (IPD).
Team Leader of R&D projects.
1998-2001
Other Employment
President and CEO
Angioceutics International, LLC
2011 - present
Founder and senior managing partner
Yolar International Hospitality, LLC
2010 - present
Dept. of Health & Human Services
Commission of Public Health.Washington D.C.
1988
Medical Consultant
HCX, Washington D.C.
1986
Vol. State of MD Emergency Medical Tech/Paramedic Assistant
BCC Rescue Squad
1982 - 1984
Courses Taught
Medical Ethics
Essential Physiology & Primer for Human Anatomy
Medical Terminology
Medical Photography
Educational Methodologies
Inter Professional Education IPE
University of Pathology Informatics Certificate of Completion Program
Lab Management University Certificate of Completion Program
Graduate Seminar - Capstone
Undergraduate Degree
Montgomery College, Rockville, MD
AA, General Education: Mathematics & Science
1984
University of Maryland, Catonsville, MD
BA, Biological Science
1986
Fellowship
National Institutes of Health (NIH), Bethesda, MD
Research Fellowship-National Eye Institute
1993 - 1998
Graduate Education
University of Maryland School of Medicine
MS, 1988, Dept. of Anatomic Pathology
Uniformed Services University of the Health Sciences (USUHS)
F. Edward Hebert School of Medicine, Bethesda, MD
PhD, 1993, Dept. of Physiology
Research Interests
Patents and Copyrights
Jacot JL, O Neill JT, Reinisch L. Noninvasive method for quantitation of oxyhemoglobin saturation by near-infrared reflectance spectrophotometry (application No. US1991000713212 filed 6/11/91, issued 6/15/93).
Sredy J, Jacot JL. Methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substituted indolealkanoic acids. (No. 99,156-A).
Vinik AI, JacotJL. Nutraceuticals for the treatment of neuropathy (submitted May 12, 2005).
Multi-year Consortium Budget Preparation and Calculation Worksheet Computer Program. Certificate of Registration, June 19, 2006.
Marketed Accomplishments
NutriNerve: A combination of several dietary supplement nutraceuticals prepackaged in a formulation designed for the treatment of neuropathies associated with diabetes.
Novel Aldose Reductase Inhibitor: Discovery of a highly potent and selective Aldose Reductase Inhibitor with IND FDA-submission and Phase I clinical trials for the treatment of chronic diabetic complications.
Awards
Outstanding Performer Scientist IPD/IDD Achievement Award (2001)
NIH Fellows Award for Research Excellence (1996)
Recipient of ARVO Travel Fellowship Grant (1994 & 1996)
Outstanding Poster Presentation Award Graduate Research Colloquium, USUHS (1992)
Honorable Mention (1990) & Recipient (1991): The Emma L. Bockman Memorial Award for Excellence in Cardiovascular/Cancer Research
Presentations and Scholarships
Selected Publications
Jacot JL, Vinik AI. Diabetic Retinopathy: Unraveling the Paradoxical Effects of Intensive Insulin Treatment. Insulin 2007, vol 2. no1. 4-11.
Jacot JL, Sherris D. Role of mTOR inhibitors in the pathophysiology of diabetic retinopathy. Journal of Ophthalmology. 2011, Article ID 589813, 19 pages.
Jacot JL, Looft-Wilson RC, Yousefieh N, Lattanzio FA, Hosseini A. The Vasoproliferative Phase in the Oxygen-Induced Rat Model of Retinopathy of Prematurity Exhibits Concomitant Increased Expression of VEGF164 and Phosphorylation of eNOS at Serine 1179 Journal of Clinical Pathology and Laboratory Medicine 2017 vol 1 , issue 1 page 12-20.
Courses Taught
Medical Ethics
Essential Physiology & Primer for Human Anatomy
Medical Terminology
Medical Photography
Educational Methodologies
Inter Professional Education IPE
University of Pathology Informatics Certificate of Completion Program
Lab Management University Certificate of Completion Program
Graduate Seminar - Capstone
Undergraduate Degree
Montgomery College, Rockville, MD
AA, General Education: Mathematics & Science
1984
University of Maryland, Catonsville, MD
BA, Biological Science
1986
Fellowship
National Institutes of Health (NIH), Bethesda, MD
Research Fellowship-National Eye Institute
1993 - 1998
Graduate Education
University of Maryland School of Medicine
MS, 1988, Dept. of Anatomic Pathology
Uniformed Services University of the Health Sciences (USUHS)
F. Edward Hebert School of Medicine, Bethesda, MD
PhD, 1993, Dept. of Physiology
Research Interests
Patents and Copyrights
Jacot JL, O Neill JT, Reinisch L. Noninvasive method for quantitation of oxyhemoglobin saturation by near-infrared reflectance spectrophotometry (application No. US1991000713212 filed 6/11/91, issued 6/15/93).
Sredy J, Jacot JL. Methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substituted indolealkanoic acids. (No. 99,156-A).
Vinik AI, JacotJL. Nutraceuticals for the treatment of neuropathy (submitted May 12, 2005).
Multi-year Consortium Budget Preparation and Calculation Worksheet Computer Program. Certificate of Registration, June 19, 2006.
Marketed Accomplishments
NutriNerve: A combination of several dietary supplement nutraceuticals prepackaged in a formulation designed for the treatment of neuropathies associated with diabetes.
Novel Aldose Reductase Inhibitor: Discovery of a highly potent and selective Aldose Reductase Inhibitor with IND FDA-submission and Phase I clinical trials for the treatment of chronic diabetic complications.
Awards
Outstanding Performer Scientist IPD/IDD Achievement Award (2001)
NIH Fellows Award for Research Excellence (1996)
Recipient of ARVO Travel Fellowship Grant (1994 & 1996)
Outstanding Poster Presentation Award Graduate Research Colloquium, USUHS (1992)
Honorable Mention (1990) & Recipient (1991): The Emma L. Bockman Memorial Award for Excellence in Cardiovascular/Cancer Research
Presentations and Scholarships
Selected Publications
Jacot JL, Vinik AI. Diabetic Retinopathy: Unraveling the Paradoxical Effects of Intensive Insulin Treatment. Insulin 2007, vol 2. no1. 4-11.
Jacot JL, Sherris D. Role of mTOR inhibitors in the pathophysiology of diabetic retinopathy. Journal of Ophthalmology. 2011, Article ID 589813, 19 pages.
Jacot JL, Looft-Wilson RC, Yousefieh N, Lattanzio FA, Hosseini A. The Vasoproliferative Phase in the Oxygen-Induced Rat Model of Retinopathy of Prematurity Exhibits Concomitant Increased Expression of VEGF164 and Phosphorylation of eNOS at Serine 1179 Journal of Clinical Pathology and Laboratory Medicine 2017 vol 1 , issue 1 page 12-20.