Research at the Jones Institute for Reproductive Medicine
The Jones Institute for Reproductive Medicine (JI) continues its tradition of cutting-edge basic science and clinically-applied research. Funding is currently being provided by the Howard and Georgeanna Jones Foundation and also from pharmaceutical industry through competitive grants.
Major projects include:
- Biology of the endometrium and implantation.
- Development of novel human implantation model (3D cell culture system) and gene regulation of embryo attachment and invasion.
- Study of the etiology of menstrual/endometrial bleeding disorders.
- 4.Characterization of granulosa cell physiology and relation to thyroid disease.
- 4-Sperm DNA fragmentation and sperm separation techniques to increase ICSI success.
- 5-Identification of biomarkers of embryo developmental competence.
- 6-Examination of factors affecting oocyte aging and its prevention.
- 7-Clinical application of egg vitrification and new PGD/PGS protocols for testing of embryo chromosomal/genetic defects.
- Large - scale research sponsored by the Agency for International Development targeted to develop new contraceptives.
- Phase l and Phase 2 clinical testing of new spermicides, microbicides, and virucidal compounds.
- New treatment modalities for endometriosis and menopause.