Linking the mechanisms of sleep, stress and disease

Stressed woman with laptop

Stress is common in modern society and can arise from incidents related to work, education, personal relationships, health, finances, and housing as well as from traumatic experiences. It is estimated that around 74% of people experience stress so severe they cannot cope with it, and that 90% of people experience at least one traumatic event over their lifetime. Stress contributes to multiple health problems including stress-related psychiatric disorders such as post-traumatic stress disorder, anxiety, insomnia, and depression and neurodegenerative disorders such as dementia or Alzheimer’s disease later in life, as well as other physiological health problems.

CINID research projects are aimed at understanding mechanisms that underlie the reciprocal influences of stress, sleep disturbances, and neuroinflammation at both the neurobiological level and as factors that underlie disease states.