Our investigators are looking at the relation between cognitive, sensory and social factors in adults with ASD. If you (or your child) are a healthy young adult between the age of 16 and 30, have a diagnosis of autism spectrum disorder and have been on stable medication for at least 4 weeks, you may be eligible to participate in the study. There are no additional costs to participate in this study. All participants will be compensated for their time. For more information about the study, please call 757.446.5176.

Donepezil's effect on cardiac function in patients with Alzheimer's disease through an in vivo, non invasive measure of peripheral neurocholinergic function: Relation to therapeutic efficacy

Protocol summary: The study will include a baseline session and 2 follow-up sessions that will take place three and six months after the initial visit. Both sessions will take no more than 90 minutes to complete. The baseline session will include informed consent, a psychosocial evaluation, medical/psychiatric history, mental and thinking tests (cognitive measures), electrocardiogram (EKG) to measure heart rate, blood pressure and a blood sample (baseline session only). Follow-up sessions will include any changes in medical history since the baseline session, mental and thinking tests and an EKG.

Basic eligibility criteria:

  • Aged 60-85
  • Taking the medication Donepezil (Aricept) for less than 2 years but have started the medication prior to the first session
  • Diagnosed with Alzheimer's disease
  • Free of heart problems such as stroke or arrhythmias

Study site location: EVMS Neuropsychology, Andrews Hall, Suite 461 (or the participant's home upon request)

Contact for further information: Lewis Hackett, MA, at 734.255.9618 or 757.446.5604. You may also contact Mr. Hackett via email at hacketlp@evms.edu.

Transcranial magnetic stimulation in treating psychiatric disorders

Protocol summary: The goal of the study is to establish a data bank with information routinely employed in clinical practice on patients receiving transcranial magnetic stimulation (TMS) for the treatment of cognitive, emotional and behavioral disorders (e.g., major depressive disorder, obsessive-compulsive disorder and post traumatic stress disorder). This data bank will be used to monitor and evaluate factors that may optimize or possibly hinder the effectiveness of TMS treatment in humans.

Basic eligibility criteria:

  • Adult (age 18-89) subject receiving TMS treatment at EVMS

Study site location: EVMS

Contact for further information: EVMS Psychiatry and Behavioral Sciences, 757.446.5888 or brainstim@evms.edu

All advertised clinical trials have been approved by the EVMS Institutional Review Board.