Gene expression and Ingenuity Pathway Analysis

Ciavarra, P., Machida, M., Lundberg, P. S., Gauronskas, P., Wellman, L. L., Steel, C., and Sanford, L. D. (2018) Controllable and uncontrollable stress differentially impact pathogenicity and survival in a mouse model of viral encephalitis. Journal of Neuroimmunology 319 (2018) 130–141.

Cardier, B, Goranson, HT, Casas, N, Lundberg, P, Erioli, A, Takaki, R, Nagy, D, and Sanford, LD. (2017) Modeling the peak of emergence in systems: Design and katachi, Prog Biophys Mol Bio 131:213-241

Cardier, B., Sanford, LD, Goranson, HT, Lundberg, P, Ciavarra, RP, Devlin, K, Cassas, N, and Erioli, A. (2017) Modeling the Resituation of Memory in Neurobiology and Narrative, AAAI Publications Science of Intelligence: Computational Principles of Natural and Artificial Intelligence, Spring 534-40, Technical Report SS-17-07

Ciavarra RP, Lundberg P, Machida M, Ambrozewicz MA, Wellman LL, Breving K, Steel C, Sanford LD. (2017) Early gene activation initiates neuroinflammation prior to VSV neuroinvasion: Impact on antiviral responses and sleep. J Neuroimmunol. Feb 15;303:31-42.

Butcher, MJ , Filipowicz, A, Waseem, TC, McGary, C, Magilnick, N, Boldin, M, Lundberg, PS, and Galkina E. (2016) Atherosclerosis-driven Treg plasticity results in the formation of a dysfunctional subset of plastic IFNγ+ Th1/Tregs. Circulation Research. 119:1190-1203.


Lassiter, B.P., A.V. Ferraioli, K.M. Cunnion, P.S. Lundberg, and N.K. Krishna (2016) Development of a Novel Flow Cytometry Based Titration Assay to Quantify Herpes Simplex Virus Type 1 (HSV-1). BioProcess. J. 15(1): XX-XX (in press)

Nguyen, T.K., C.N. Nelson, J.R. Woody, and P.S. Lundberg. (2012) Changes in Herpes Simplex Virus Gene Expression Due to Commercial Serum Source and Indicator Dye in the Growth Medium.BioProcess. J. 11(1): 22-28

Sequence analysis

Wortman, M.J., P.S. Lundberg, A.V. Dagdanova, P. Venkataraman, D.C. Daniel, E.M. Johnson (2016) Opportunistic DNA Recombination with Epstein-Barr Virus at Sites of Control Region Rearrangements Mediating JC Virus Neurovirulence. J. Infect Dis.; doi: 10.1093/infdis/jiv755

Johnson, E.M., M.J. Wortman, P.S. Lundberg and D.C. Daniel (2015) Orderly Steps in Progression of JC Virus to Virulence in the Brain. Brain Disord Ther, S2-003; doi: 10.4172/2168-975X.S2-003

Johnson, E.M., M.J. Wortman, A.V. Dagdanova, P.S. Lundberg, and D.C. Daniel. (2013) Polyomavirus JC in the Context of Immunosuppression: A Series of Adaptive, DNA Replication-Driven Recombination Events in the Development of Progressive Multifocal Leukoencephalopathy. Clin. Dev. Immunol. 2013:197807.

Ouburg S, J.M. Lyons, J.A. Land, J.E. den Hartog, J.S. Fennema, H.J. de Vries, C.A. Bruggeman, J.I. Ito, A.S. Peña, P.S. Lundberg, and S.A. Morré. (2009) TLR9 KO mice, haplotypes and CPG indices in Chlamydia trachomatis infection. Drugs Today (Barc). 45 Suppl B:83-93.

Genetic and pathogen analysis

Ramakrishna C., A. Ferraioli, A. Calle, T.K. Nguyen, H. Openshaw, P.S. Lundberg, P. Lomonte, and E. M. Cantin (2015) Establishment of HSV1 Latency in Immunodeficient Mice Facilitates Efficient In Vivo Reactivation. PLoS Pathog 11(3): e1004730. doi:10.1371/journal. ppat.1004730

Sanders, M. S., G. Th. J., van Well, S. Ouburg; P. S. J. Lundberg; A. M. van Furth, S. A. Morre. (2011) Single Nucleotide Polymorphisms in TLR9 Are Highly Associated with Susceptibility to Bacterial Meningitis in Children. Clin. Infect. Dis. 52: 475-480.

Lundberg, P., C. Ramakrishna, J. Brown, J. M. Tyszka, M. Hamamura, D. R. Hinton, S. Kovats, O. Nalcioglu, K. Weinberg, H. Openshaw, and E. M. Cantin. (2008) The immune response to herpes simplex virus type 1 infection in susceptible mice is a major cause of central nervous system pathology resulting in fatal encephalitis. J. Virol. 82:7078-88.

Lundberg, P., H. Openshaw, M. Wang, H.-J. Yang and E. Cantin (2007) Effects of CXCR3 Signaling on Development of Fatal Encephalitis, Corneal and Periocular Skin Disease in HSV-1 Infected Mice is Mouse Strain Dependent. I.O.V.S., 48(9): 4162-4170.

Lundberg, P., P. V. Welander, C. K. Edwards, N. v. Rooijen, and E. Cantin. (2007) Tumor Necrosis Factor (TNF) Protects Resistant C57BL/6 Mice Against Herpes Simplex Virus-Induced Encephalitis Independently of Signaling Via TNFR1 or TNFR2. J. Virol., 81(3): p.1451-60.

siRNA design, miR discovery and in vivo verification

Ciavarra, R.P., M. Machida, T. Weaver, A. Pearson, K. Kennedy, M. Yu, P.S. Lundberg, and L.D. Sanford. (2016) Controllable and Uncontrollable Stress Differentially Regulate CNS Antiviral Immune Responses and Pathogenesis Brain, Behavior Imm (submitted)

Lundberg, P., H-J Yang, S-J Jung, M. A. Behlke, S.D. Rose, and E. M. Cantin. (2012) Protection against TNF-Dependent Liver Toxicity by Intraperitoneal Liposome Delivered DsiRNA Targeting TNFα In Vivo. J. Control. Release. 160(2):194-199.

Amarzguioui, M., P. Lundberg, E. Cantin, J. Hagstrom, M. Behlke and J. J. Rossi. (2006) Rational design and in vitro/in vivo delivery of Dicer substrate siRNAs. Nature Protocols, published online: doi:10.1038/nprot.2006.72

Kim, D.-H., M. Longo, Y. Han, P. Lundberg, E. Cantin and J. J. Rossi. (2004) Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nature Biotech. 22(3):321-325.

PCR optimization and evaluation

Welander, P., E. Cantin, and P. Lundberg. (2011) Using Taguchi-Based Statistics To Produce Robust PCR Results. Bioproc. J. 10(1): 22-26.

Lundberg, P., P. Welander, H. Openshaw, C. K. Edwards, C. Nalbandian, L. Moldawer and. E. M. Cantin. (2003) A Locus On Mouse Chromosome 6 That Determines Resistance To Herpes Simplex Virus Also Influences Reactivation, While an Unlinked Locus Augments Resistance of Female Mice. J. Virol 77(21):11661-11673.