Jerry L. Nadler, MD, FACP, FAHA, FACE Relevant Publications

  1. Green-Mitchell SH, Cazares LH, Semmes OJ, Nadler JL, Nyalwidhe JO.  On-tissue identification of insulin: In situ reduction coupled with mass spectrometry imaging.Proteomics Clin Appl. 2011 Aug;5(7-8):448-53. Epub 2011 Jun 8. doi: 10.1002/prca.201000152. 
  2. Galkina E, Butcher M, Keller SR, Goff M, Bruce A, Pei H, Sarembock IJ, Sanders JM, Nagelin MH, Srinivasan S, Kulkarni RN, Hedrick CC, Lattanzio FA, Dobrian AD, Nadler JL, Ley K. Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1. Arterioscler Thromb Vasc Biol. 2011 Dec 22. [Epub ahead of print].
  3. Cole BK, Kuhn NS, Green-Mitchell SM, Leone KA, Raab RM, Nadler JL, Chakrabarti SK. 12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response. Am J Physiol Endocrinol Metab. 2012 Mar;302(6):E654-65. doi: 10.1152/ ajpendo.00373. 2011.Epub 2012 Jan 3.
  4. Tersey SA, Carter JD, Rosenberg L, Taylor-FishwickDA, Mirmira RG, Nadler JL. Amelioration of type 1 diabetes following treatment of non-obese diabetic mice with INGAP and lisofylline. Journal of Diabetes Mellitus. Vol.2, No.2, 251-257 (2012). Pub Date: May 25, 2012.
  5. Taylor-Fishwick DA, Weaver JR, Grzesik W, Chakrabarti S, Green-Mitchell S,  Imai Y, Kuhn N, Nadler JL. Production and function of IL-12 in islets and beta cells.  Diabetologia. 2013 Jan;56(1):126-35.
  6. Green-Mitchell SM, Tersey SA, Cole BK, Ma K, Leone KA, Maybee NA, Chakrabarti SK, McDuffie M, Taylor-Fishwick DA, Mirmira RG, Nadler JL, Morris MA.  Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development. PLoS One, 2013;8(2):e56763. Epub 2013 Feb 21.
  7. Imai Y, Dobrian AD, Morris MA, Nadler JL. Islet inflammation: A unifying target for diabetes treatment? Trends Endocrinol Metab. 2013 Feb 25.
  8. Dobrian AD, Galkina EV, Ma Q, Hatcher M, Aye SM, Butcher MJ, Ma K, Haynes BA, Kaplan MH, Nadler JL. STAT4 deficiency reduces obesity-induced insulin resistance and adipose tissue inflammation.  Diabetes. 2013 Dec;62(12):4109-21. Epub 2013 Aug 12. PMCID: PMC3837053 [Available on 2014/12/1].
  9. Luci DK, Jameson JB, Yasgar A, Diaz G, Joshi N, Kantz A, Markham K, Perry S, Kuhn NS,  Yeung J,  Kerns EH, Schultz L, Holinstat M, Nadler JL, Taylor-Fishwick DA, Jadhav A, Simeonov A, Holman T,  Maloney DJ. Synthesis and Structure-Activity Relationship Studies of 4-((2-hydroxy-3-methoxybenzyl)amino) benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase. J Med Chem. 2014 Jan 6. [Epub ahead of print].
  10. Butcher MJ, Hallinger D, Garcia EM, Machida Y, Chakrabarti S, NadlerJL, Galkina EV, Imai, Y. Association of proinflammatory cytokines and islet resident leukocytes with islet dysfunction in type 2 diabetes. Diabetologia. 2014 Jan 16. [Epub ahead of print].