Research at the Jones Institute for Reproductive Medicine

The Jones Institute for Reproductive Medicine (JI) continues its tradition of cutting-edge basic science and clinically-applied research. Funding is currently being provided by the Howard and Georgeanna Jones Foundation and also from pharmaceutical industry through competitive grants.

Major projects include:

• Biology of the endometrium and implantation.
• Development of novel human implantation model (3D cell culture system) and gene regulation of embryo attachment and invasion.
• Study of the etiology of menstrual/endometrial bleeding disorders.
• 4.Characterization of granulosa cell physiology and relation to thyroid disease.
• 4-Sperm DNA fragmentation and sperm separation techniques to increase ICSI success.
• 5-Identification of biomarkers of embryo developmental competence.
• 6-Examination of factors affecting oocyte aging and its prevention.
• 7-Clinical application of egg vitrification and new PGD/PGS protocols for testing of embryo chromosomal/genetic defects.
• Large - scale research sponsored by the Agency for International Development targeted to develop new contraceptives.
• Phase l and Phase 2 clinical testing of new spermicides, microbicides, and virucidal compounds.
• New treatment modalities for endometriosis and menopause.