Professional Experiences

• Eastern Virginia Medical School, Associate Dean for Continuing Medical Education, 1995-present
• Eastern Virginia Medical School, Associate Dean for Research and Academic Planning, 1990-1995
• Eastern Virginia Medical School, Chairman, Pharmacology, 1987-1997
• Eastern Virginia Medical School, Interim Associate Dean for Research and Academic Planning, 1989-1990
• Eastern Virginia Medical School, Acting Chairman, Pharmacology, 1986-1987
• Eastern Virginia Medical School, Interim Chairman, Pharmacology, 1984
• Old Dominion University, Adjunct Professor, Chemistry, 1983-present
• Co-Director, Therapeutic Drug Monitoring Laboratory, EVMS, 1982-present
• Eastern Virginia Medical School, Professor, Pharmacology, 1979-present
• Eastern Virginia Medical School, Associate Professor, Pharmacology, 1977-1979
• Old Dominion University, Adjunct Associate Professor, Chemistry, 1978-1982
• University of Massachusetts Medical School, Associate Professor, Pharmacology, 1974-1977
• University of Massachusetts Medical School, Assistant Professor, Physiology and Biochemistry, 1971-1977
• Dartmouth Medical School, Visiting Assistant Professor, Department of Pharmacology and Toxicology, 1972-1974
• Dartmouth Medical School, Post-doctoral Fellow Department of Pharmacology and Toxicology, 1970-1971
• Sterling-Winthrop Research Institute, Rensselaer, New York, Assistant Research Biologist, Pharmacology, 1962-1966

Education

• Ph.D., SUNY, Upstate Medical Center, Syracuse, New York, 1970
• M.S., College of St. Rose, Albany, New York, 1966
• B.S., St. Bernadine of Siena College, Loudonville, New York, 1962

Publications

Loewy, D., Williams, P.B., Crouch, E. and Cooke, W.J. Systemic aminocaproic acid significantly increases antifibrinolysis in aqueous humor. Arch. Ophthal. 105: 272-276, 1987.

Castle, M.C. and Cooke, W.J. Measurement of Vitamin E in serum and plasma by high-performance liquid chromatograpy with electro-chemical detection. Therap. Drug Monitoring 7:364-368, 1985.

Cooke, W.J. and Cooke, L. Biliary and urinary excretion of tyropanoic acid and its metabolites in the dog. Invest. Radiol. 18:285-292, 1983.

Cooke, W.J. and Cooke, L. Effects of anesthetic agents on the hepatic metabolism and biliary secretion of iopanoic acid enantiomers in rat. J. Pharmacol. Exp. Ther. 225:85-93, 1983.

Cooke, W.J., Zuckerman, B. and Schneider, F.H. Hydrolysis of centrophenoxine in tissue culture media: Analysis by high pressure liquid chromatography. Age 2:13-16, 1979.

Cooke, W. J. and Cooke, L. Effects of anesthetic agents on the biliary excretion of iopanoate in the rat. Drug Met. Dispos. 5:377-393, 1977.

Cooke, W.J. and Munck, L. Biliary excretion of iopanoate glucuronide in the rat. Drug Met. Dispos. 5:368-376, 1977.

Cooke, W.J. A small inexpensive anesthetic apparatus for rats. J. App. Physiol. 41:429-430, 1976.

Mudge, G.H. and Cooke, W.J. Oral cholecystography: Osmotic activity of iopanoic glucuronide in bile. Johns Hopkins Med. J. 137:65-68, 1975.

Cooke, W.J. and Mudge, G.H. Effect of choloretics on biliary and urinary excretion of cholecystographic agents. Invest. Radiol. 10:189-196, 1975.

Cooke, W.J. and Mudge, G.H. Effect of choloretics on biliary and urinary excretion of cholecystographic agents. Invest. Radiol. 10:25-34, 1975.

Cooke, W.J., Berndt, W.O. and Mudge, G.H. Effect of biliary stasis and hepatotoxins on the excretion of iopanoate in the rat. J. Pharmacol. Exp. Therap. 192:618-629, 1975.

Mudge, G.H., Cooke, W.J. and Berndt, W.O. Electrolyte excretion and free-water production during onset of acute diuresis. Am. J. Physiol. 228:1304-1312, 1975.

Mudge, G.H., Berndt, W.O. and Cooke, W.J. Renal excretion of urea in the dog during onset and subsidence of diuresis. Am. J. Physiol. 227:369-376, 1974.

Cooke, W.J., Berndt, W.O. and Mudge, G.H. Effects of phenobarbital and taurocholate on biliary excretion of iopanoate and iophenoxate in the rat. J. Pharmacol. Exp. Therap. 187:158- 168.

Cooke, W.J. and Robinson, J.D. Factors influencing choline movements in rat brain slices. Biochem. Pharmacol. 20:2355-2366, 1971.

Cooke, W.J. and Robinson, J.D. Factors influencing 45Ca metabolism in brain and other organs in vivo. Proc. Soc. Exp. Biol. Med. 138:906-912, 1971.

Cooke, W.J. and Robinson, J.D. Factors influencing calcium movements in brain slices. Am. J. Physiol. 221:218-225, 1971.

Cooke, W.J. and Robinson, J.D. On the uptake of hexoses by rat cortical slices. J. Neurochem. 18:1351-1356, 1971.

Rosenberg, F.J., Cooke, W.J. and Wessinger, G.D. The effect of central nervous system depressants on the tolerance to local anesthetic solutions. Int. J. Surg. 55:79-88, 1971.

Cooke, W.J. Biochemical Studies on the movement of calcium and choline in neural tissue. Ph.D. Thesis, Department of Pharmacology, Upstate Medical Center, State University of New York, Syracuse, New York, 1970.

Rosenberg, F.J. and Cooke, W.J. A peripheral component of centrally acting muscle relaxants: Chloromezanone and mephenisin. J. Pharmacol. Exp. Therap. 155:145-151, 1967.

Cooke, W.J. An efficient nerve-muscle preparation for the study of pharmacological agents, M.S. Thesis, College of St. Rose, Albany, New York, 1966.

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