Professional Experiences

• Professor, Biochemistry (Tenured), Eastern Virginia Medical School, 1988-present
• Professor, Biochemistry, Eastern Virginia Medical School, 1988-present
• Adjunct Associate Professor, Chemistry, Old Dominion University, 1982-1986
• Associate Professor, Biochemistry, Eastern Virginia Medical School, 1981-1988
• Assistant Professor, Biochemistry, Eastern Virginia Medical School, 1977-1981
• Adjunct Assistant Professor, Chemistry, Old Dominion University, 1978-1981
• Postdoctoral Fellow, Department of Nutrition, Harvard School of Public Health, 1974-1977

Education

• Postdoctoral, School of Public Health, Harvard University, Cambridge, Massachusetts, 1974-1977
• Ph.D., Brandeis University, Waltham, Massachusetts, 1970-1974
• M.A., Brandeis University, Waltham, Massachusetts, 1963-1968
• B.A., Swarthmore College, Swarthmore, Pennsylvania, 1959-1963

Publications

• Glew RH and Rosenthal MD, 2007 editors. "Clinical Studies in Medical Biochemistry, 3rd edition," Oxford University Press.
• Pepe GJ and Rosenthal MD. 2007 Congenital Adrenal Hyperplasia: P450C21 Steroid Hydroxylase Deficiency. in: Glew RH and Rosenthal MD (eds): "Clinical Studies in Medical Biochemistry, 3rd edition," Oxford University Press, pp. 89-100.
• Proud VK, Rosenthal MD. (2007) MHG-CoA Lyase Deficiency. in: Glew RH and Rosenthal MD (eds): "Clinical Studies in Medical Biochemistry, 3rd edition," Oxford University Press, pp. 217-225.
• Rosenthal MD and Pasquienelli LM (2007 Obesity: Growing Problem. in: Glew RH and Rosenthal MD (eds): "Clinical Studies in Medical Biochemistry, 3rd edition," Oxford University Press, pp. 245-254.
• Rosenthal MD, Albrecht ED, Pepe GJ. (2004) Estrogen modulates developmentally regulated gene expression in fetal baboon liver. Endocrine. 23(2-3): 219-228.
• Rosenthal MD, Albrecht ED, Pepe GJ. (2001) Developmental maturation of primate placenthal trophoblast: placental cytosolic and secretory phosphilipase A2 expression after estrogen suppression of baboons. Prostaglandins Other Lipid Mediat. 66(3):155-163.
• Rosenthal MD, Albrecht ED, and Pepe GJ. (1998) Developmental maturation of baboon placental trophoblast: Expression of messenger ribonucleic acid and protein levels of cytosolic and secretory phospholipases A2. J. Clin. Endocrinol. Metab. 83:2861-2869.
• Rzigalinski BA, Blackmore PF, and Rosenthal MD.  (1996) Arachidonate mobilization is coupled to depletion of intracellular calcium stores and influx of extracellular calcium in differentiated U937 cells. Biochim. Biophys. Acta. 1299:342-352.
• Rosenthal MD, Gordon MN, Buescher ES, Slusser JH, Harris LK, and Franson RC. (1995) Human neutrophils store type II 14-kDa phospholipase A2 in granules and secrete active enzyme in response to soluble stimuli. Biochem. Biophys. Res. Commun. 208:650-656.
• Rzigalinski BA and Rosenthal MD. (1994) Effects of DMSO-induced differentiation on arachidonate mobilization in the human histiocytic lymphoma cell line U937: Responsiveness to sub-micromolar calcium ionophore A23187 and phorbol esters. Biochem. Biophys. Acta 1223, 219-225.
• Rosenthal MD and Franson RC. (1994) Separation of agonist-stimulated arachidonate mobilization from subsequent leukotriene B4 synthesis in human neutrophils: Different effects of oleoylacetylglycerol and phorbol myristate acetate as priming agents. J. Cell. Physiol. 160, 522-530.
• Rosenthal MD, Lattanzio KS, and Franson RC. (1996). 1,3-Dioctanoylglycerol modulates arachidonate mobilization in human neutrophils and its inhibition by PGBx: Evidence for a protein kinase C-independent role of diacylglycerols in signal transduction. Biochem. Biophys. Acta, 1177, 79-86.
• Franson RC, Harris, LK, Ghosh SS, and Rosenthal MD. (1992) Sphingolipid metabolism and signal transduction: Inhibition of in vitro phospholipase activity by sphingosine. Biochem. Biophys. Acta, 1136, 169-174.
• Rosenthal MD, Lattanzio KS, and Franson RC. (1992) The effects of the phospholipase A2 inhibitors aristolochic acid and PGBx on A23187-stimulated mobilization of arachidonate in human neutrophils are overcome by diacylglycerol or phorbol ester. Biochem. Biophys. Acta, 1126, 319-326.
• Garcia MC, Mueller HW, and Rosenthal MD. (1991) C20 polyunsaturated fatty acids and phorbol myristate acetate enhance agonist-stimulated synthesis of 1-radyl-2-acetyl-sn-glycero-3-phosphocholine in vascular endothelial cells. Biochem. Biophys. Acta, 1083. 37-45.
• Rosenthal MD, Garcia MC, Jones MR, and Sprecher H. (1991) Retroconversion and delta-4 desaturation of docosatetraenoate (22:4(n-6)) and docosapentaenoate (22:5(n-3)) by human cells in culture. Biochem. Biophys. Acta 1083, 29-36.
• Garcia MC, Sprecher H, and Rosenthal MD. (1990) Chain elongation of polyunsaturated fatty acids by vascular endothelial cells: Studies with arachidonate analogues. Lipids 25, 211-215.
• Rosenthal MD and Franson, RC. (1989) Oligomers of prostaglandin B1 inhibit arachidonate mobilization in human neutrophils and endothelial cells. Biochem. Biophys. Acta, 1006, 278-286.
• Franson, RC and Rosenthal MD. (1989) Oligomers of prostaglandin B1 inhibit in vitro phospholipase A2 activity. Biochem. Biophys. Acta, 1006, 272-277.
• Rosenthal MD, Garcia MC, and Sprecher H. (1989) Substrate specificity of the agonist-stimulated release of polyunsaturated fatty acids from vascular endothelial cells. Arch. Biochem. Biophys. 274, 590-600.
• Rosenthal MD, Vishwanath BS, and Franson RC. (1989) Effects of aristolochic acid on phospholipase A2 activity and arachidonate metabolism in human neutrophils. Biochem. Biophys. Acta 1001: 1-8.
• Rosenthal MD, Morris E, and Jones JE. (1988) Esterification of 8,11,14-eicosatrienoate and arachidonate into alkylacyl- and diacylglycerophosphocholine by vascular endothelial cells. Lipids 23:1089-1092.

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