Professional Experiences

• Research Assistant Professor, Eastern Virginia Medical School, Department of Physiological Sciences
• Postdoctoral Fellow, Eastern Virginia Medical School, Department of Physiological Sciences
• Research Associate, Eastern Virginia Medical School, Department of Microbiology and Molecular Cell Biology
• Research Associate, University of Texas Southwestern Medical Center at Dallas, Hamon Center for Therapeutic Oncology
• Research Assistant, University of Texas Medical Branch at Galveston, Sealy Center for Molecular Science

Education

• Postdoctoral Fellow, Eastern Virginia Medical School, Department of Physiological Sciences
• Ph.D., Eotvos Lorand University, National Institute of Oncology, Budapest, Hungary
• M.S., Eotvos Lorand University, Budapest, Hungary

Teaching

• Medical Biochemistry (small group), 2006-present.

Memberships

• Biophysical Society

Awards

• Postdoctoral Fellowship, American Heart Association, 2005-2007
• Travel Grant, International Biophysics Congress in Montpellier, France. National Academies and Biophysical Society, 2005

Publications

• Forgacs E, Cartwright S, Kovacs M, Sakamoto T, Sellers JR, Corrie JE, Webb MR, White HD. Kinetics of ADP dissociation from the trail and lead heads of actomyosinv following the power-stroke. J Biol Chem. 2008 Jan 11;283(2):766-73. Epub 2007 Oct 27.

• Forgacs E, Cartwright S, Kovacs M, Sakamoto T, Sellers JR, Corrie JE, Webb MR, and White HD. Kinetic mechanism of myosin V-S1 using a new fluorescent ATP analog. Biochemistry 2006:45(43):13035-45.

• Forgacs E, Gupta SK, Kerry JA, and Semmes OJ. The bZIP transcription factor ATFx binds human T-cell leukemia virus type 1 (HTLV-1) Tax and represses HTLV-1 long terminal repeat-mediated transcription. J Virol. 2005; 79(11):6932-9.

• Burbee DG, Forgacs E, Zochbauer-Muller S, Shivakumar L, Fong K, Gao B, Randle D, Kondo M, Virmani A, Bader S, Sekido Y, Latif F, Milchgrub S, Toyooka S, Gazdar AF, Lerman MI, Zabarovsky E, White M, and Minna JD. Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J Natl Cancer Inst. 2001;93(9):691-9.

• Forgacs E, Wren JD, Kamibayashi C, Kondo M, Xu XL, Markowitz S, Tomlinson GE, Muller CY, Gazdar AF, Garner HR, and Minna JD. Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers. Oncogene. 2001;20(8):1005-9.

• Forgacs E, Zochbauer-Muller S, Olah E, and Minna JD. Molecular genetic abnormalities in the pathogenesis of human lung cancer. Pathol Oncol Res. 2001;7(1):6-13.

• Lokeshwar VB, Rubinowicz D, Schroeder GL, Forgacs E, Minna JD, Block NL, Nadji M, and Lokeshwar BL. Stromal and epithelial expression of tumor markers hyaluronic acid and HYAL1 hyaluronidase in prostate cancer. J Biol Chem. 2001;276(15)11922-32.

• Latham GJ, Forgacs E, Beard WA, Prasad R, Bebenek K, Kunkel TA, Wilson SH, and Lloyd RS. Vertical-scanning mutagenesis of a critical tryptophan in the “minor groove binding track” of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove. J Biol Chem. 2000;275(20):15025-33.

• Gao B, Sekido Y, Maximov A, Saad M, Forgacs E, Latif F, Wei MH, Lerman M, Lee JH, Perez-Reyes E, Bezprozvanny I, and Minna JD. Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2). J Biol Chem. 2000;275(16):12237-42.

• Liu CX, Musco S, Lisitsina NM, Forgacs E, Minna JD, and Listisyn NA. LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines. Cancer Res. 2000;60(7):1961-7.

• Wren JD, Forgacs E, Fondon JW 3rd, Pertsemlidis A, Cheng SY, Gallardo T, Williams RS, Shohet RV, Minna JD, and Garner HR. Repeat polymorphisms with gene regions: phenotypic and evolutionary implications. Am J Hum Genet. 2000;67(2):345-56.

• Forgacs E, Biesterveld EJ, Sekido Y, Fong K, Muneer S, Wistuba II, Milchgrub S, Brezinschek R, Virmani A, Gazdar AF, and Minna JD. Mutation analysis of the PTEN/MMAC1 gene in lung cancer. Oncogene. 1998;17(12):1557-83.

• Lin WM, Forgacs E, Warshal DP, Yeh IT, Martin JS, Ashfaq R, and Muller CY. Loss of heterozygosity and mutational analysis of the PTEN/MMAC1 gene in synchronous endometrial and ovarian carcinomas. Clin Cancer Res. 1998;4(11):2577-83.

• Forgacs E, Latham F, Beard WA, Prasad R, Bebenek, K, Kunkel AT, Wilson SH, and Lloyd RS. Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts. J Biol Chem. 1997;272(13):8525-30.

Research Interests

• Actomyosin interactions
• Structure and mechanism of myosin VIIA
• Walking mechanism of myosinV

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