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National Center for Collaboration in
Medical Modeling and Simulation

Founding Partners

Eastern Virginia Medical School LogoEastern Virginia Medical School

Founded in 1973, and located in Norfolk, Virginia, Eastern Virginia Medical School has internationally recognized programs in standardized patient simulation and is a founding partner of the National Center for Collaboration in Medical Modeling and Simulation (NCCMMS).

The Theresa A. Thomas Professional Skills Teaching and Assessment Center of EVMS is an international leader in its broad use of Standardized (Simulated) Patients (SPs) and provides its services on a contract basis to a number of external clients, including other medical schools, health professions programs, meetings of professional associations and others.

As further evidence of its preeminence in its field, the Theresa A. Thomas Center in July of 2003 hosted the first stand-alone conference of the Association of Standardized Patient Educators (ASPE). As medical education moves toward significantly increased community-based training and medical students are placed in primary care preceptorships, the Skills Center helps to ensure consistency in learning outcomes.

The mission of the Skills Center is to teach and assess clinical competencies in medical interviewing, clinical reasoning, ethical dilemmas, communication skills, physical examination and the application of clinical knowledge. The Skills Center has SPs ages 16-78, including Physical Teaching Assistants and Genital Teaching Assistants who receive additional training in using their bodies in teaching, assessment, and providing feedback on physical examinations.

Recent related EVMS research includes improving the utilization of Standardized Patients in medical education; modeling the effects of Centers for Disease Control category A through C biological agents/pathogens that could potentially be utilized as weapons of mass destruction; several programs to model gene expression in breast cancer and other diseases; the utilization of simulation in emergency medical services training; the use of simulation to teach biofeedback approaches to improving circulation in diabetics; and the use of simulation to assist older patients with daily tasks such as driving.

In addition, EVMS basic scientists in the Department of Microbiology and Molecular Cell Biology have significant experience with developing models of physiological processes and proteomics. O. John Semmes, Ph.D., leads a team of researchers actively engaged in applying state-of-the-art proteomics to clinical and basic science questions, including proteomic modeling methodologies utilizing SELDI-TOF Mass Spectrometry to monitor the immune response to influenza vaccination. These methodologies are essential for developing more effective vaccines against natural or bioterrorism-induced influenza infections, and have the potential for identifying asymptomatic deploying military personnel who are in the early stages of influenza infection to prevent the spread of the illness throughout the military unit.

Timothy J. Bos, Ph.D., and his research team are focusing on modeling the characteristics of the AP-1 oncoprotein with respect to the structural and functional properties required for transformation, as well as identification and characterization of specific AP-1-regulated target genes that may be involved in oncogenesis. These diverse AP-1 complexes bind and regulate the expression of target genes involved in many different biological processes including cell growth, differentiation, apoptosis, and tumorigenesis. The biological consequences attributed to AP-1 activity are directly related to specific and directed patterns of gene expression.

Richard R. Drake, Ph.D., and his team have, among other areas, conducted research on Herpesvirus Thymidine Kinase Gene (HSV-TK) Therapy. The primary focus of this effort is to model and improve gene therapy applications of the HSV-TK gene for the treatment of cancers, especially those of the prostate, colon and breast.

Kenneth D. Somers, Ph.D., and his research team have developed a model of head and neck cancer in the mouse based on orthotopic implantation of tumor cells. The model should be useful in mechanistic studies of tumor invasion and metastasis.

Michael Fabrizio, M.D., EVMS Associate Professor of Urology, and his colleagues are regional pioneers in Robotic Surgery through utilizing the da Vinci® Surgical System robot developed by Intuitive Surgical to perform radical prostatectomy surgery in which the prostate gland is removed. The da Vinci® robot improves patient outcomes and provides surgeons with greater precision, eliminating hand tremors, increasing range of motion, and enhancing visualization during surgery. The robotic system allows Dr. Fabrizio's hand movements to be translated into precise movements of micro-instruments within the operative site by the da Vinci® robot.

Leonard Weireter, Jr., M.D., EVMS Professor of Surgery, is working closely with colleagues at EVMS and at Old Dominion University on two medical modeling and simulation projects. The first is to model how a region such as Hampton Roads would handle the medical aspects of a Medical Mass Casualty situation such as may be caused by the use of weapons of mass destruction by terrorists. The second project involves the development of a Wound Debridement Simulator that would provide realistic training experience for medical personnel, both regular military and reserve, who do not have the opportunity to practice the wound debridement procedure on a regular basis but may be called upon to undertake this procedure on the battlefield.

Thomas Hubbard, M.D., J.D., EVMS Professor of Clinical Pediatrics, is the EVMS team leader on the Augmented Standardized Patient project being developed in conjunction with researchers from Old Dominion University. The Augmented Standardized Patient project will enable individuals who realistically portray patients (standardized patients) for medical student training to utilize technology to simulate abnormal physical findings such as abnormal heart and/or lung sounds, thus expanding the range of abnormalities that can be portrayed in the teaching process.


Old Dominion University LogoOld Dominion University

Old Dominion University (ODU) is located in Norfolk, Virginia and was originally founded in 1930 as a division of the College of William and Mary. Today, ODU is one of only 101 public universities designated as Carnegie/Doctoral Research-Extensive institutions.

Recognizing the significance of the modeling and simulation enterprise in Hampton Roads (see below) and the need to provide an academic infrastructure to support this activity, ODU began to plan and solicit support for research and graduate programs in modeling and simulation during Spring 1995. The University was assisted in these efforts by the Virginia Center for Innovative Technology (CIT), Virginia's Secretary for Commerce and Trade, the Hampton Roads Economic Development Alliance, and the City of Suffolk.

In October 1996, ODU entered into a Cooperative Research and Development Agreement (CRADA) with the U.S. Joint Forces Command. This CRADA, coupled with special funding from the Commonwealth of Virginia, facilitated the establishment of the Virginia Modeling, Analysis and Simulation Center (VMASC) on July 1, 1997. This was followed quickly by the development of formal degree programs in modeling and simulation, a master's degree program in Fall 1998 and a doctoral degree program in Spring 2000 (which recently produced the world's first Ph.D. in modeling and simulation). Due to these efforts, ODU has rapidly gained recognition as one of the dominant academic institutions in the modeling and simulation area.

Today, VMASC is a not-for-profit collaborative enterprise center of ODU's College of Engineering and Technology that partners with academia, industry and government to advance modeling, simulation, and visualization research, development and education and that seeks to leverage, promote, and cultivate simulation technology expertise through industry, government and academia. VMASC's vision is to be a global leader in modeling and simulation (M&S) research and development and an integrator of M&S with visualization technologies. VMASC will also be a portal for the nation's premier M&S educational programs.

VMASC has a proven track record in advancing and adapting military, government, and industrial modeling and simulation technologies and is actively extending these to medical training and to the delivery of medical services through its involvement with the NCCMMS. In addition, VMASC has previously worked with local and regional governments as well as with the U.S. Joint Forces Command to develop and implement simulations that address training in command and control in response to events (e.g., a hurricane) that could produce mass casualties.

VMASC/NCCMMS Faculty

Mark W. Scerbo is a Professor of Human Factors Psychology at Old Dominion University and Co-Director of the NCCMMS. He leads a team of researchers and developers who are working to validate medical simulators, develop new simulation models and technology, integrate simulation into medical school curricula, and develop models for regional response to mass casualty events.

James P. Bliss is an Associate Professor in the Psychology Department at ODU. He is currently researching alarm mistrust and the effectiveness of alarms in automobiles and aircraft. He is the recipient of Young Faculty Research Symposium Minigrant Continuation Award and the UAH Foundation Award for Research and Creative Achievement.

Lee A. Belfore II is an Associate Professor of Electrical and Computer Engineering at Old Dominion University. He has been a Licensed Professional Engineer (VA) since 2001 and received his Modeling and Simulation Professional Certification in 2002. Since 1982, he has worked in both industry and academia in various areas including fault-tolerant computing, automatic diagnosis, data compression, artificial neural networks, interactive virtual reality, modeling and simulation. His current research interests include devising an extensible framework for developing interactive virtual environments for medical applications.

Frederic D. McKenzie is an Associate Professor of Electrical and Computer Engineering at Old Dominion University where he currently serves as Principal Investigator (PI) and Co-PI on projects involving medical modeling and simulation, behavior representation in simulations, and simulation architectures. He has over 10 years of research and development experience in the software and artificial intelligence fields, including object-oriented design and knowledge-based systems. Both his M.S. and Ph.D. work have been in artificial intelligence focusing on knowledge representation and model-based diagnostic reasoning.

VMASC Research Scientists

John A. Sokolowski has served as a Senior Research Scientist at VMASC since 2001. His research interests include human behavior modeling, decision system modeling, multiagent system simulation, and modeling and simulation for homeland security. He is a published author and a member of the Society for Modeling and Simulation International, American Association of Artificial Intelligence, Association of Computing Machinery, Phi Kappa Phi, and Phi Beta Kappa.

Jennifer Seevnick has been a Research Scientist at VMASC since 2001. Her areas of expertise include virtual and augmented environments, visualization and multimedia training for medicine, engineering, architecture, science and art. Research project involvement currently includes project management, research and development for simulations and multimedia training materials, technology studies and data visualization. She has been project manager of the NCCMMS Wound Debridement surgical trainer since March 2004, and has been lead prototype developer since its inception in March 2003.

Hector M. Garcia is a research scientist at ODU/VMASC and helped to set up the VMASC-end EAST Virtual Environments Laboratory. He has six years experience working on Silicon Graphics Super Computers and high visualization cluster systems. He is a team member for the development of a Virtual Environment for training on an ONR grant project for a check-point scenario simulation using shared collaborative environments.

Yuzhong Shen is a Senior Research Scientist at VMASC. His research interests include visualization and computer graphics, urban terrain database generation, battlefield modeling and simulation, signal processing, and computing systems. His work at VMASC includes medical modeling and simulation, oceanography visualization, and graduate course development.

Students

Elizabeth A Schmidt is a doctoral student in Human Factors Psychology who has studied skill acquisition with medical simulators and contextual performance effects in virtual environments. She is currently applying human factors methods and techniques to the design of an instructional simulator for wound debridement.

Hope S. Hanner-Bailey is a doctoral student in Industrial-Organizational Psychology who has studied skill acquisition with medical simulators as well as methods for assessing performance with low fidelity simulators and in virtual environments. For her dissertation, she is using competency modeling to describe surgical excellence.

Emre Baydogan is a doctoral student in Electrical and Computer Engineering. He is currently working on development of simulator prototypes. His research will include devising a framework that will support multiple virtual reality platforms methodologies architectures supporting the synthesis of virtual reality applications.

Saurav Mazumdar is a doctoral student in Electrical and Computer Engineering. His research will include determining how to optimally assimilate content from different virtual reality platforms.

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