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Ph.D. in Biomedical
Sciences Course Descriptions
BP718/818. Introduction to the Laboratory. 2 credits.
Intensive laboratory course introducing students to basic research techniques, including DNA purification,
subcloning, polymerase chain reaction, and cell culture methods.
BP717/817. Research Techniques. 2 credits.
Lectures covering topics in molecular cloning and analysis,
detection systems including PCR and real time PCR, working with
proteins, basics of cell culture.
BP722/822. BioInformatics. 1 credit.
Introduction to basic concepts in bioinformatics. Use of Incogen and
Vector NTI software and tools on the NCBI website. Lecture and
computer laboratory will cover topics such as DNA analysis tools,
PCR primer design, motif analysis, similarity searches, restriction
enzyme analysis, multiple sequence alignments, protein sequence
identification, phylogenetic tools and public databases.
BP 723/823. Gene Manipulation and Expression. 1 credit.
Methods of gene manipulation and mutagenesis. Lecture and laboratory
topics include deletion and site directed mutagenesis, chimeras, use
of linkers and expression tags, as well as SDS polyacrylamide gel
electrophoresis, in vitro transcription and translation, cell
culture, transfection and methods of protein analysis.
BP 724/824 DNA Sequencing and Analysis. 1 credit.
Lecture topics will focus on methods of manual and automated DNA
sequencing as well as sequence analysis tools. The laboratory will
focus on automated DNA sequencing including, setup of sequence
reactions, capillary loading and analysis. A computer lab component
will instruct students on open reading frame analysis, contiguous
sequence alignments, restriction enzyme mapping and a variety of
database tools.
BP741/841. Introduction to the Research Literature. 1 credit.
Designed to train students in the interpretation of research
literature. Students will assess the introduction, methods, results
and discussion sections of journal articles.
BP733/833. Concepts in Cell Biology and Physiology. 3 credits.
Prerequisite: BP702/802. An overview of selected topics in
contemporary cell and molecular biology and physiology, including
the molecular basis of normal and aberrant cell growth, immunology,
cytoskeleton, cell adhesion and extracellular matrix, signal
transduction, and renal, cardiovascular and reproductive physiology.
BP773/873. Responsible Conduct in Science. 1 credit.
Series of lectures exposing graduate students to moral and ethical
dilemmas in biomedical sciences. The course will also expose
students to peer review processes related to submission of grants
and manuscripts.
BP719/819, 729/820, 821/822. Biomedical Sciences Lab Rotation I,
II, III. 2 credits each.
Laboratory rotations with a pre-designated faculty member in which
the student obtains hands-on experience. Designed for students to
sample different types of research models, techniques, and subject
matter.
BP732/832. Biomedical Sciences Seminar (Journal Club). 1 credit.
Pass/fail grading only.
Seminar presentations by students in various research areas: e.g.,
tumor biology, infectious diseases, immunology, molecular cell
biology, cardiovascular and reproductive physiology, endocrinology
and neuroscience. Journal articles describing major scientific
advancements are discussed and critiqued. (Offered fall and spring
each year)
BP798. Research. 1-6 credits.
Laboratory research leading to preparation of a M.S. thesis.
BP799. Thesis. 1-6 credits.
Review of the literature, analysis of data and writing the M.S.
thesis.
BP895. Special Topics in Biomedical Sciences. 1-3 credits.
Guided readings and discussions of current research topics.
Prerequisites: approval of program director and instructor.
BP898. Research. 1-6 credits.
Laboratory research leading to preparation of a Ph.D. dissertation.
BP899. Dissertation. 1-6 credits.
Review of the literature, analysis of data and writing the Ph.D.
dissertation.
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