Julius O. Nyalwidhe, Ph.D. - Publications

The search for biomarkers of human embryo developmental potential in IVF: a comprehensive proteomic approach.

Nyalwidhe J, Burch T, Bocca S, Cazares L, Green-Mitchell S, Cooke M, Birdsall P, Basu G, Semmes OJ, Oehninger S.

Mol Hum Reprod. 2012 Dec 17. [Epub ahead of print]

PMID: 23247814 [PubMed - as supplied by publisher]

Identification of Differentially Expressed Proteins in Direct Expressed Prostatic Secretions of Men with Organ-confined Versus Extracapsular Prostate Cancer.

Kim Y, Ignatchenko V, Yao CQ, Kalatskaya I, Nyalwidhe JO, Lance RS, Gramolini AO, Troyer DA, Stein LD, Boutros PC, Medin JA, Semmes OJ, Drake RR, Kislinger T.

Mol Cell Proteomics. 2012 Dec;11(12):1870-84. doi: 10.1074/mcp.M112.017889. Epub 2012 Sep 17.

PMID: 22986220 [PubMed - in process]

Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tactic.

Sharp JA, Echague CG, Hair PS, Ward MD, Nyalwidhe JO, Geoghegan JA, Foster TJ, Cunnion KM.

PLoS One. 2012;7(5):e38407. doi: 10.1371/journal.pone.0038407. Epub 2012 May 31.

PMID: 22675461 [PubMed - indexed for MEDLINE] Free PMC Article

Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus.

Hair PS, Echague CG, Rohn RD, Krishna NK, Nyalwidhe JO, Cunnion KM.

J Transl Med. 2012 Mar 5;10:35. doi: 10.1186/1479-5876-10-35.

PMID: 22390383 [PubMed - indexed for MEDLINE] Free PMC Article

Identification of prostate-enriched proteins by in-depth proteomic analyses of expressed prostatic secretions in urine.

Principe S, Kim Y, Fontana S, Ignatchenko V, Nyalwidhe JO, Lance RS, Troyer DA, Alessandro R, Semmes OJ, Kislinger T, Drake RR, Medin JA.

J Proteome Res. 2012 Apr 6;11(4):2386-96. doi: 10.1021/pr2011236. Epub 2012 Feb 29.

PMID: 22339264 [PubMed - indexed for MEDLINE]

Complement regulator C4BP binds to Staphylococcus aureus and decreases opsonization.

Hair PS, Wagner SM, Friederich PT, Drake RR, Nyalwidhe JO, Cunnion KM.

Mol Immunol. 2012 Apr;50(4):253-61. doi: 10.1016/j.molimm.2012.01.010. Epub 2012 Feb 12.

PMID: 22333221 [PubMed - indexed for MEDLINE]

On-tissue identification of insulin: in situ reduction coupled with mass spectrometry imaging.

Green-Mitchell SM, Cazares LH, Semmes OJ, Nadler JL, Nyalwidhe JO.

Proteomics Clin Appl. 2011 Aug;5(7-8):448-53. doi: 10.1002/prca.201000152. Epub 2011 Jun 8.

PMID: 21656913 [PubMed - indexed for MEDLINE] Free PMC Article

Protease inhibitors decrease IgG shedding from Staphylococcus aureus, increasing complement activation and phagocytosis efficiency.

Fernandez Falcon MF, Echague CG, Hair PS, Nyalwidhe JO, Cunnion KM.

J Med Microbiol. 2011 Oct;60(Pt 10):1415-22. doi: 10.1099/jmm.0.027557-0. Epub 2011 Jun 2.

PMID: 21636671 [PubMed - indexed for MEDLINE]

Targeted identification of metastasis-associated cell-surface sialoglycoproteins in prostate cancer.

Yang L, Nyalwidhe JO, Guo S, Drake RR, Semmes OJ.

Mol Cell Proteomics. 2011 Jun;10(6):M110.007294. doi: 10.1074/mcp.M110.007294. Epub 2011 Mar 29.

PMID: 21447706 [PubMed - indexed for MEDLINE] Free PMC Article

Enhancement in MALDI-TOF MS analysis of the low molecular weight human serum proteome.

Gatlin CL, White KY, Tracy MB, Wilkins CE, Semmes OJ, Nyalwidhe JO, Drake RR, Malyarenko DI.

J Mass Spectrom. 2011 Jan;46(1):85-9. doi: 10.1002/jms.1864. No abstract available.

PMID: 21190259 [PubMed - indexed for MEDLINE] Free PMC Article

The viral oncoprotein tax sequesters DNA damage response factors by tethering MDC1 to chromatin.

Belgnaoui SM, Fryrear KA, Nyalwidhe JO, Guo X, Semmes OJ.

J Biol Chem. 2010 Oct 22;285(43):32897-905. doi: 10.1074/jbc.M110.146373. Epub 2010 Aug 20.

PMID: 20729195 [PubMed - indexed for MEDLINE] Free PMC Article

Potent inhibition of the classical pathway of complement by a novel C1q-binding peptide derived from the human astrovirus coat protein.

Gronemus JQ, Hair PS, Crawford KB, Nyalwidhe JO, Cunnion KM, Krishna NK.

Mol Immunol. 2010 Nov-Dec;48(1-3):305-13. doi: 10.1016/j.molimm.2010.07.012. Epub 2010 Aug 21.

PMID: 20728940 [PubMed - indexed for MEDLINE]

Interdependent phosphorylation within the kinase domain T-loop Regulates CHK2 activity.

Guo X, Ward MD, Tiedebohl JB, Oden YM, Nyalwidhe JO, Semmes OJ.

J Biol Chem. 2010 Oct 22;285(43):33348-57. doi: 10.1074/jbc.M110.149609. Epub 2010 Aug 16.

PMID: 20713355 [PubMed - indexed for MEDLINE] Free PMC Article

Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole.

Azimzadeh O, Sow C, Gèze M, Nyalwidhe J, Florent I.

Malar J. 2010 Jun 30;9:189. doi: 10.1186/1475-2875-9-189.

PMID: 20591164 [PubMed - indexed for MEDLINE] Free PMC Article

In-depth proteomic analyses of direct expressed prostatic secretions.

Drake RR, Elschenbroich S, Lopez-Perez O, Kim Y, Ignatchenko V, Ignatchenko A, Nyalwidhe JO, Basu G, Wilkins CE, Gjurich B, Lance RS, Semmes OJ, Medin JA, Kislinger T.

J Proteome Res. 2010 May 7;9(5):2109-16. doi: 10.1021/pr1001498.

PMID: 20334419 [PubMed - indexed for MEDLINE] Free PMC Article

Comprehensive proteome profiling of the Fe(III)-reducing myxobacterium Anaeromyxobacter dehalogenans 2CP-C during growth with fumarate and ferric citrate.

Chao TC, Kalinowski J, Nyalwidhe J, Hansmeier N.

Proteomics. 2010 Apr;10(8):1673-84. doi: 10.1002/pmic.200900687.

PMID: 20162560 [PubMed - indexed for MEDLINE]

The identification of serum biomarkers of high-let radiation exposure and biological sequelae.

Britten RA, Mitchell S, Johnson AM, Singletary SJ, Keeney SK, Nyalwidhe JO, Karbassi ID, Lonart G, Sanford LD, Drake RR.

Health Phys. 2010 Feb;98(2):196-203. doi: 10.1097/HP.0b013e3181acff7c.

PMID: 20065683 [PubMed - indexed for MEDLINE]

Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue.

Cazares LH, Troyer D, Mendrinos S, Lance RA, Nyalwidhe JO, Beydoun HA, Clements MA, Drake RR, Semmes OJ.

Clin Cancer Res. 2009 Sep 1;15(17):5541-51. doi: 10.1158/1078-0432.CCR-08-2892. Epub 2009 Aug 18.

PMID: 19690195 [PubMed - indexed for MEDLINE] Free Article

Proteomic expression profiling and identification of serum proteins using immobilized trypsin beads with MALDI-TOF/TOF.

Karbassi ID, Nyalwidhe JO, Wilkins CE, Cazares LH, Lance RS, Semmes OJ, Drake RR.

J Proteome Res. 2009 Sep;8(9):4182-92. doi: 10.1021/pr800836c.

PMID: 19603828 [PubMed - indexed for MEDLINE]

Serum proteomic biomarker discovery reflective of stage and obesity in breast cancer patients.

Schaub NP, Jones KJ, Nyalwidhe JO, Cazares LH, Karbassi ID, Semmes OJ, Feliberti EC, Perry RR, Drake RR.

J Am Coll Surg. 2009 May;208(5):970-8; discussion 978-80. doi: 10.1016/j.jamcollsurg.2008.12.024. Epub 2009 Mar 26.

PMID: 19476873 [PubMed - indexed for MEDLINE]

Clinical collection and protein properties of expressed prostatic secretions as a source for biomarkers of prostatic disease.

Drake RR, White KY, Fuller TW, Igwe E, Clements MA, Nyalwidhe JO, Given RW, Lance RS, Semmes OJ.

J Proteomics. 2009 Aug 20;72(6):907-17. doi: 10.1016/j.jprot.2009.01.007. Epub 2009 Jan 20. Review.

PMID: 19457353 [PubMed - indexed for MEDLINE] Free PMC Article

Glycomic characterization of prostate-specific antigen and prostatic acid phosphatase in prostate cancer and benign disease seminal plasma fluids.

White KY, Rodemich L, Nyalwidhe JO, Comunale MA, Clements MA, Lance RS, Schellhammer PF, Mehta AS, Semmes OJ, Drake RR.

J Proteome Res. 2009 Feb;8(2):620-30. doi: 10.1021/pr8007545.

PMID: 19128049 [PubMed - indexed for MEDLINE] Free PMC Article

Complementation of a phycocyanin-bilin lyase from Synechocystis sp. PCC 6803 with a nucleomorph-encoded open reading frame from the cryptophyte Guillardia theta.

Bolte K, Kawach O, Prechtl J, Gruenheit N, Nyalwidhe J, Maier UG.

BMC Plant Biol. 2008 May 16;8:56. doi: 10.1186/1471-2229-8-56.

PMID: 18485196 [PubMed - indexed for MEDLINE] Free PMC Article

McArthur revisited: fluorescence microscopes for field diagnostics.

Jones D, Nyalwidhe J, Tetley L, Barrett MP.

Trends Parasitol. 2007 Oct;23(10):468-9. Epub 2007 Sep 7.

PMID: 17826338 [PubMed - indexed for MEDLINE]

Use of biotin derivatives to probe conformational changes in proteins.

Azim-Zadeh O, Hillebrecht A, Linne U, Marahiel MA, Klebe G, Lingelbach K, Nyalwidhe J.

J Biol Chem. 2007 Jul 27;282(30):21609-17. Epub 2007 Jun 1.

PMID: 17545162 [PubMed - indexed for MEDLINE] Free Article

A proteomic approach towards the analysis of salt tolerance in Rhizobium etli and Sinorhizobium meliloti strains.

Shamseldin A, Nyalwidhe J, Werner D.

Curr Microbiol. 2006 May;52(5):333-9. Epub 2006 Apr 7.

PMID: 16604415 [PubMed - indexed for MEDLINE]

Proteases and chaperones are the most abundant proteins in the parasitophorous vacuole of Plasmodium falciparum-infected erythrocytes.

Nyalwidhe J, Lingelbach K.

Proteomics. 2006 Mar;6(5):1563-73.

PMID: 16470785 [PubMed - indexed for MEDLINE]

Intracellular parasitism: cell biological adaptations of parasitic protozoa to a life inside cells.

Nyalwidhe J, Maier UG, Lingelbach K.

Zoology (Jena). 2003;106(4):341-8.

PMID: 16351918 [PubMed]

A biotin derivative blocks parasite induced novel permeation pathways in Plasmodium falciparum-infected erythrocytes.

Baumeister S, Endermann T, Charpian S, Nyalwidhe J, Duranton C, Huber S, Kirk K, Lang F, Lingelbach K.

Mol Biochem Parasitol. 2003 Nov;132(1):35-45.

PMID: 14563535 [PubMed - indexed for MEDLINE]

A nonpermeant biotin derivative gains access to the parasitophorous vacuole in Plasmodium falciparum-infected erythrocytes permeabilized with streptolysin O.

Nyalwidhe J, Baumeister S, Hibbs AR, Tawill S, Papakrivos J, Volker U, Lingelbach K.

J Biol Chem. 2002 Oct 18;277(42):40005-11. Epub 2002 Aug 16.

PMID: 12186876 [PubMed - indexed for MEDLINE] Free Article

Antifolate drug resistance and point mutations in Plasmodium falciparum in Kenya.

Khan B, Omar S, Kanyara JN, Warren-Perry M, Nyalwidhe J, Peterson DS, Wellems T, Kaniaru S, Gitonga J, Mulaa FJ, Koech DK.

Trans R Soc Trop Med Hyg. 1997 Jul-Aug;91(4):456-60.

PMID: 9373654 [PubMed - indexed for MEDLINE]